SERUM TEST

‘This profile screens for the two most common antibodies against streptococcus, DNase antibodies in serum (ADB); antistreptolysin O titer (ASO). These antibodies may cross-react with brain tissue causing abnormal behaviors. Both of these tests are performed to identify a previous infection of group A beta-hemolytic Streptococcus. These infections cause rheumatic fever or a kidney disease called glomerulonephritis, poststreptococcal versions of these diseases, as well as scarlet fever.

Recently, high titers of these antibodies have been associated with PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections) and with autism, Tourette syndrome, tic disorder, Parkinson's disease, and OCD.’

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